Ahead of an October 2025 broadcast, the upcoming My Friend's Little Sister Has It In for Me! anime unveiled a brand-new teaser trailer and visual highlighting Iroha's cheekiness and the rom-com series' core cast. My Friend's Little Sister Has It In for Me! Teaser Trailer My Friend's Little Sister Has It In for Me! Teaser Visual My Friend's Little Sister Has It In for Me! 's currently confirmed cast is as follows: Iroha Kohinata voiced by Sayumi Suzushiro Akiteru Oboshi voiced by Haruki Ishiya Mashiro Tsukinomori voiced by Tomori Kusunoki Ozuma Kohinata voiced by Soma Saito Sumire Kageishi voiced by Kana Hanazawa RELATED: My Friend's Little Sister Has It In for Me! TV Anime Debuts in October 2025 Kazuomi Koga ( Rent-a-Girlfriend ) directs the My Friend's Little Sister Has It In for Me! anime at studio BLADE, with Toko Machida ( With You and the Rain ) on series composition, Katsuyuki Sato ( Hokkaido Gals Are Super Adorable! ) on character designs and Tsugumi Tanaka, Kaho Sawada, Kanade Sakuma and Hanae Nakamura on music. J-Novel publishes an official English version of Ghost Mikawa and Tomari's original light novel series, describing the story like so: If a girl teases you, that means she likes you! Unfortunately, Akiteru knows from experience that isn’t the case. Because every girl he interacts with shows him nothing but scorn, and he’s not scored a single date from it! Luckily, he’s more concerned with securing a spot for him and his game-development buddies at his uncle’s business. But when his uncle throws him a condition that involves playing the part of his daughter’s boyfriend, Akiteru has no choice but to take it. What will his best friend’s sister Iroha, who bullies him relentlessly, think of the news? Source: Comic Natalie
